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Georgios Skiniotis, PhD, has been appointed to develop and lead the newly created Center of Excellence for Structural Cell Biology. The center will advance understanding of cell biology from the atom…

The University of Michigan Rogel Cancer Center has named Kyle Cuneo, MD, its new associate director for clinical research. In addition, a new position of assistant director for clinical research will…

Masonic Cancer Center (MCC) has announced that Jeffrey Miller, MD, (pictured) will serve as the center’s interim director. MCC extends its deep appreciation to Douglas Yee, MD, for his leadership ove…

Huntsman Cancer Institute (HCI) at the University of Utah announces the appointment of Deanna Kepka, PhD, MPH, investigator at HCI and professor in the College of Nursing, as the inaugural leader of …

Marci Lee Nilsen, PhD, RN, CHPN, FAAN, is the new co-lead of UPMC Hillman Cancer Center's Biobehavioral Cancer Control program. Dr. Nilsen is also director of the Head and Neck Cancer Survivorship Pr…

The GW Cancer Center announces the addition of Prashanth Ashok Kumar, MD, to its hematologist-oncologist team. With a background in thoracic oncology, Dr. Ashok Kumar brings a wealth of expertise in …

Breast cancer surgeon Tari A. King, MD, FACS, FSSO, FASCO, has been appointed chief surgical officer for the cancer service line at Winship Cancer Institute and Emory Healthcare. She will also serve …

Moffitt Cancer Center and its wholly owned subsidiary SPEROS FL, a 775-acre global innovation campus, has announced Josh Carpenter, D.Phil., as the president of Speros and Moffitt’s chief integration…

Tracy Smith, PhD, (pictured) has joined Ashish Deshmukh, PhD, as a co-leader of the Cancer Prevention and Control Research Program at MUSC Hollings Cancer Center. Dr. Smith's research focuses on redu…

Jenny Freedman, PhD, member of the Duke Cancer Institute Center for Prostate and Urologic Cancers, explains how a natural gene-splicing process can run amok, producing prostate cancer cells. Dr. Free…

Training the next generation of cancer researchers is essential for the cancer research enterprise. However, training programs and methods to evaluate their effectiveness vary greatly across the USA …

A University of Arizona Health Sciences-led study found that patients are more likely to get colonoscopies following abnormal stool test results if patient navigators assist them through the process.…

Histone lysine demethylases, or KDMs, were first documented in 2004 in a groundbreaking study that led to new understandings about the genetic mechanisms of cancer and other diseases. Now, researcher…

In a study co-led by the University of Maryland School of Medicine, researchers have identified a "master regulator" gene, ZNFX1, that may act as a biomarker to help guide treatment in future clinica…

Scientists at UC San Diego—in collaboration with researchers at Stanford University, Harvard Medical School, and the University of British Columbia—have created a comprehensive, interactive map of U2…

Older adults with cancer respond just as well as younger patients to immune checkpoint inhibitors despite age-related immune system differences, according to a study by researchers from the Johns Hop…

A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, has identified a novel oncometabolite that accumulates in tumors and impairs…

A team of UK Markey Cancer Center researchers have found the mechanism that grants prostate cancer resistance to enzalutamide. Prostate cancer patients who don’t respond to usual hormonal treatments …

Treatment resistance and relapse in the most common type of lung cancer can be traced to a protein called agrin, according to a preclinical study led by Roswell Park Comprehensive Cancer Center.

A recent study sheds new light on the prevalence of positive lung cancer screenings in patients following a low-dose chest CT (LDCT) for lung cancer screening. The research compared clinical screenin…

UF Health Cancer Center researchers have discovered a crucial mechanism by which a common gene mutation leads to resistance against platinum-based chemotherapy in non-small cell lung cancer.

UK Markey Cancer Center researchers have identified a mechanism by which a gut hormone contributes to fatty liver disease, offering potential new targets for treating the common condition. The study …

In the mid-2000s, when a team of researchers led by Dennis Slamon, MD, PhD, and Richard Finn, MD, began investigating a compound developed by Pfizer called PD-0332991, few thought it would fly. Today…

An editorial argues that patients with resectable non-small cell lung cancer who achieve a complete pathological response after neoadjuvant chemoimmunotherapy should still receive adjuvant immunother…

Researchers at Baylor College of Medicine, Texas Children’s Hospital, the Hospital for Sick Children in Toronto, and collaborating institutions have discovered a novel line of communication between m…

Looking beyond DNA, Fred Hutch and Memorial Sloan Kettering Cancer Center scientists found that common RNA splicing-factor mutations in myelodysplastic syndrome and acute myeloid leukemia cells creat…

Stanford Medicine scientists are using artificial intelligence to better capture how healthy cells surrounding tumors influence cancer cell behavior and how those interactions can inform treatments.

In the 1960s, astronauts returned from microgravity with decreased bone density. This decrease revealed that bones must undergo constant stress to grow and maintain themselves. Survivors of childhood…

The latest UCSF research has reexamined immunotherapy clinical trial data on bladder and skin cancer and found that "cold" tumors, ones that haven’t yet been infiltrated by immune cells, are just as …

Nearly half of Americans who smoke use menthol cigarettes, which are harder to quit. A new University of Michigan study will test the best way to help menthol cigarette smokers break that habit. The …

Researchers at The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute and Memorial Sloan Kettering Cancer Center in New York have found a link bet…

A nationwide team led by researchers at Baylor College of Medicine, Texas Children’s Hospital, and UPMC Children's Hospital of Pittsburgh has proposed a major revision to how Langerhans cell histiocy…

In 2021, a provision in the 21st Century Cures act took effect which required that all medical test results be released to a patient’s electronic medical record as soon as they become available. As a…

Two new studies led by Washington University physician-scientist Stephen T. Oh, MD, PhD, at Siteman Cancer Center have identified a possible way to block the progression of several forms of blood can…

A new study led by UCLA Health Jonsson Comprehensive Cancer Center has found that many cases of high-risk nonmetastatic hormone-sensitive prostate cancer may be more advanced than previously thought.…

Investigators from Baylor College of Medicine, Texas Children’s Cancer and Hematology Center, the Center for Cell and Gene Therapy at Baylor, Houston Methodist Hospital, and Texas Children’s Hospital…

Keck Medicine of USC is participating in a national, multisite clinical trial examining if a water vapor system that uses small, targeted amounts of steam to kill cancer cells is a safe and effective…

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new st…

Women who develop bacterial vaginosis (BV) often later acquire chlamydia. Now, researchers at Albert Einstein College of Medicine, Roswell Park Comprehensive Cancer Center, and the Icahn School of Me…

Compared with other forms of breast cancer, triple-negative breast cancer (TNBC) is more likely to have spread at the time of diagnosis and is more likely to recur, largely because it becomes resista…

A non-opioid investigational drug with promising pre-clinical results in treating neuropathic pain has passed an important hurdle after the study’s safety review committee reviewed the data from init…

Researchers at The Tisch Cancer Institute at Mount Sinai, in collaboration with Memorial Sloan Kettering Cancer Center, have developed a new tool that could change the way cancer patients are treated…

UK Markey Cancer Center researchers have discovered a promising new way to combat therapy-resistant cancers by targeting a specific protein modification.

A new study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of the University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificia…

Mount Sinai scientists have made a breakthrough in treating a type of liver cancer called hepatocellular carcinoma. The research tested a combination of treatments that could help patients live longe…

A new artificial intelligence (AI) tool developed by Stanford cancer faculty members combines data from medical images with text to predict cancer prognoses and treatment responses.

A first-of-its-kind new cancer test has been developed at the University of Michigan. MyHPVscore is a highly accurate blood test that can detect human papilloma virus-related head and neck cancer by …

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and—due to innovations in manufacturing—could make future cellular immunotherapies less expensive and more accessible to pati…

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A new study provides insights into how medulloblastoma can arise as the cerebellum develops. Researchers at Baylor College of Medicine, Texas Children’s Cancer Center, University of Toronto, St. Jude…

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Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified key metabolic mechanisms that squamous cell skin cancers use to resist treatment,…

A nurse-led initiative at the Vanderbilt Breast Center has set up a system so that women identified at high risk for breast cancer have greater opportunities for recommended follow-up screenings and …

Using a new workflow that integrates spatial transcriptomics and machine learning for imaging analysis and integration with single-cell datasets, researchers at the Johns Hopkins Kimmel Cancer Center…

Scientists at Huntsman Cancer Institute at the University of Utah have made a significant breakthrough in predicting the prognosis of triple-negative breast cancer (TNBC). Their research has led to t…

Every year, more than 22,000 patients in the U.S. undergo a potentially lifesaving blood stem cell transplant. But historically, some patients with blood cancers have been less likely than others to …

An international panel of top cancer doctors led by UVA Health experts has identified indicators that reflect the effectiveness of coordinated team care to improve outcomes for patients with brain me…

Staging of patients with early pancreatic cancer is inaccurate as much as 80 percent of the time, according to a new Cedars-Sinai Cancer study. The finding underscores the urgent need for advancement…

Scientists from St. Jude Children’s Research Hospital, Seattle Children’s, and the Children’s Oncology Group have identified novel genetic variations that influence relapse risk in children with stan…

Researchers at Baylor College of Medicine and collaborating institutions have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patie…

Results from a clinical trial by the ECOG-ACRIN Cancer Research Group show a striking improvement for patients who received chemotherapy before surgery to remove advanced squamous cell-type cancer of…

Researchers have published a report on pathogenic germline variants in DNA repair genes and how these inherited genetic variants might impact both the risk of developing multiple myeloma and patient …

An international clinical trial, called NATALEE, has led to the U.S. Food and Drug Administration approving ribociclib in combination with hormonal therapy for the adjuvant treatment of HR-positive, …

Results from a new UK Markey Cancer Center study show that molecular tumor boards can play an important role in identifying potential inherited cancer risks, leading to better patient care. Specifica…

People with operable non-small cell lung cancers may fare better over the next few years by receiving immunotherapy treatments before and after surgery instead of only before surgery, according to a …

Two recent scientific papers about optimal treatment of older patients with cancer not only improves clinical care but also demonstrates Wilmot Cancer Institute’s international leadership in this gro…

A Phase I/II clinical trial for patients with metastatic kidney cancer demonstrated that a novel two-agent treatment regimen developed at Roswell Park Comprehensive Cancer Center more than doubled pr…

A new therapeutic agent discovered and developed at The Ohio State University will soon be used for cancer treatment at the patient’s bedside as part of a clinical trial. Jabez Biosciences is the ind…

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also—in a particular subset of T cells—cause mitochondrial stress, DNA damage, and cell death, Vanderbilt Univer…

Members of Fox Chase Cancer Center's Office of Clinical Research (OCR), pictured, presented two aspects of their work during a poster session at AACI's 16th Annual Clinical Research Innovation (CRI) …

A toxin in the bacteria that is one of the most common causes of foodborne illness accelerates the spread of colorectal tumors to other parts of the body, a study led by UF Health Cancer Center resea…

Investigators from Cedars-Sinai and the University of California, San Francisco have identified a new way to deliver instructions that tell stem cells to grow into specific bodily structures, a criti…

A recent UK Markey Cancer Center study highlights a radiation therapy technique that treats brain tumors while preserving patients’ cognitive function. The treatment approach could offer hope for pat…

CORRECTION: This story's source was misidentified in the December 2024 AACI Update. Researchers from the Medical College of Wisconsin Cancer Center, The Tisch Cancer Institute at Mount Sinai, and Tr…

Roswell Park researchers have found significant benefits of resistance training for patients with multiple myeloma. A study, led by Jens Hillengass, MD, PhD, and Janine Joseph, MS, MBA, presents new …

Stanford Cancer Institute researchers have created a genetic screening tool that harnesses CRISPR, a gene-editing technology, to uncover genes that may be involved in doxorubicin-induced heart damage…

The human papillomavirus (HPV) accounts for 70 percent of all throat cancers now the most common type of HPV-related cancer according to the National Cancer Institute. However, the majority of Americ…

A group of scientists at VCU Massey Comprehensive Cancer Center has revealed a new genetic code that acts like a cancer ringleader, recruiting and deploying a gang of tumor cells to incite a biologic…

Clinical trials testing cancer immunotherapies have significantly under-represented Black patients. While these treatments have resulted in dramatically improved outcomes for some patients, researche…

Researchers at the University of Kentucky are exploring new ways to use nanoparticles in combination with other materials as an innovative approach to cancer therapy. The team focused on nanozymes, a…

Investigators have found that West African genetic ancestry was associated with shorter disease-free survival, particularly for women with hormone receptor-positive/human epidermal growth factor rece…

Physician-researchers with City of Hope®, led by Scott E. James, MD, PhD, have developed a way to add features to T cells to help them overcome mechanisms of chimeric antigen receptor (CAR) T cell th…

Adding the chemotherapy pill temozolomide to radiation treatment significantly improves survival for adults with brain tumors known as grade 2 gliomas, a clinical trial led by David Schiff, MD, has f…

About a third of patients with diffuse large B-cell lymphoma (DLBCL) will see their disease advance or recur following treatment. Seeking a new treatment that might boost the effectiveness of existin…

A research study led by members of the Duke University Nicholas School of the Environment and the Duke Cancer Institute aims to tackle the issue of cancer risk among firefighters based on their expos…

For cancers of organs like the liver, the long-term impact of our diet has been well studied, giving us guidance about red meat, wine, and other delicacies. A new study from researchers at University…

A Phase II clinical trial led by researchers at Winship Cancer Institute of Emory University has demonstrated that cabozantinib, a targeted therapy currently approved for advanced kidney cancer, may …

UCLA scientists have identified a potential new strategy for treating glioblastoma by reprogramming aggressive cancer cells into harmless ones. The findings demonstrate that combining radiation thera…

University of Chicago Medicine Comprehensive Cancer Center researchers demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-ne…

A study by researchers from the University of Michigan, Dana Farber Cancer Institute, and the Medical University of Vienna, shows that high-grade glioma tumor cells harboring DNA alterations in the g…

A team of scientists at VCU Massey Comprehensive Cancer Center has discovered a new combination therapy —sotorasib and an experimental drug called FGTI-2734—that overcomes drug resistance and makes t…

Multiple new cell surface targets are being investigated in advanced prostate cancer to hopefully lead to more effective therapies. Andrew Armstrong, MD, director of research for the Duke Cancer Inst…

Zotatifin, which was developed by UCSF researchers, is currently being tested against breast cancer. The latest research shows it also might work against prostate and other cancers.

A study funded by the National Cancer Institute and led by researchers at Huntsman Cancer Institute at the University of Utah shows that a personalized, clinic-aligned exercise program significantly …

A new study by University of Arizona Health Sciences researchers found that an immunotherapy previously shown to be ineffective against prostate cancer may have therapeutic potential when combined wi…

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of progenitor cells that reside in fallopian tube supportive tissue, or stroma…

Researchers at The Tisch Cancer Institute report on a personalized multi-peptide neoantigen cancer vaccine called PGV001, using relatively few antigens that induced a strong immune response across mu…

Huntsman Cancer Institute at the University of Utah broke ground on its second comprehensive cancer center on April 8. Situated in Vineyard, the new site will reduce travel time by more than an hour …

The West Virginia University (WVU) Health System has unveiled a new round of projects totaling more than $460 million that will further expand access to health care in West Virginia and create hundre…

Michigan residents impacted by cancer have a new resource to help address the financial burden and the waste of unused cancer medication. YesRx coordinates and supports Cancer Drug Repository Program…